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Quantitative Analysis

定量分析

Na Li/Professor ;

李娜 /教授 ;

College of Chemistry and Molecular Engineering

化学与分子工程学院

李娜 /教授 ;

College of Chemistry and Molecular Engineering

化学与分子工程学院

Course Description

Analytical Chemistry I, formerly called Quantitative Chemical Analysis, is one of the basic courses required for chemistry-majored undergraduates. The course is lectured for the firstyear undergraduates and provides the students with principles and basic methods as well as practical examples in solving analytical chemistry problems. It covers Introduction to Analytical Chemistry, Data Handling and Analysis, Volumetric Titrations, Gravimetry, Molecular Spectroscopy including UV-Visible Spectroscopy, Molecular Fluorescence and Phosphorescence , Infrared Analysis and Introduction to Raman Spectroscopy as well as Sample Preparation for Analytical Chemistry. Together with Analytical Chemistry II, former called Instrumental Analysis, the course provided a complete lecture series on Analytical Chemistry required for undergraduate students.Syllabus

Chapter 1 Introduction to Analytical Chemistry (1 lectur e hour)Scope and applications of analytical chemistry; basic calculation

Chapter 2 Data Process and Analysis (3 lecture hours)

Errors in chemical analysis; some important terms; systematic errors; random errors in chemical analysis; the nature of random errors; statistical treatment of random errors; standard deviation of calculated results; report computed data;Statistical data treatment and evaluation; confidence intervals; tatistical aids to hypothesis testing; analysis of variance; detection of gross errors; sampling, standardization, and calibration.

Chapter 3 Acid-base Equilibria and Neutralization T itration (6 lecture hours)

Aqueous solutions and chemical equilibria; effect of electrolytes on chemical equilibria; solving equilibrium problems for complex systems; the composition of acid/base solution as a function of pH; calculating pH of acid/base solution; acid-base buffer; neutralization titrations (monoprotic & polyprotic); calculation of titration error; application examples.

Chapter 4 Complexation and Complexometric T itration (3 lecture hours)

Complexation equilibria; Principle for complexation titration; selective itration; application of complexation titration of electrochemical cells; calculating redox equilibrium constant; constructing redox titration curves; applications of oxidation/ reduction titrations.

Chapter 5 Oxidization-Reduction Equilibria and Redox T itration (2 lecture hours)

Oxidation/reduction reactions in electrochemical cells; Nernst equation, electrode potentials; application of standard electrode potential; calculating potentials of electrochemical cells; calculating redox equilibrium constant; constructing redox titration curves; applications of oxidation/ reduction titrations.

Chapter 6 Precipitation Equilibria, Precipitation Titration Gravimetry (1 lecture hour)

Precipitation equilibria; titration by forming precipitation; obtaining precipitation in order to determine sample by weighing; the key to success for this two methods.

Chapter 7 Spectrophotometry (9 lecture hours)

Light and its interaction with matter; mechanism of molecular absorption, fluorescence and phosphorescence, Raman scattering; type of transition and absorption with organic compound; polar solvent on absorption pectra with instrumentation; mechanism of molecular absorption, fluorescence and phosphorescence, as well as Raman scattering; Instrumentations for UV-vis spectrophotometer, fluorimeter, FTIR spectrophotometer, Raman spectrometer.

Chapter 9 Introduction of Separation Methods in Quantitative Analysis (2 lecture hours)

Introduction; Precipitation based separation; Solvent extraction

Chapter 10 Solving Real Analytical Pr oblems (1 lecture hour)

Examples to illustrate how to solve a real analytical problem

Homework due date: Before 5:00 PM on each lecture day Two notebooks for homework, with name and student ID Office Hours: to be decided at the beginning of the course Summative assessment: Mid-Term 35%; final 50%; homework 10%; term paper or Oral Presentation 5% on given topics

Reference Books:

1. Quantitative Chemical Analysis. Na Li J.J. Hefferren Ke’an Li Peking University Press,2009

2. Analytical Chemistry Course, Edited by Li Ke’an, Peking University Press, 2005

3. Analytical Chemistry Course – Pr oblems and Solutions, Edited by Li Ke’an, Peking University Press, 2006

4. Analytical Chemistry—The Concise Textbook of Quantitative Chemical Analysis (Third Edition). Peng Chonghui, Feng Jianzhang, Zhang Xiyu, Li Ke’an and Zhao Fenglin, Peking University Pr ess, 2009

5. Concise Textbook of Quantitative Chemical Analysis (Second Edition). Peng Chonghui, Feng Jianzhang, Zhang Xiyu, Li Ke’an and Zhao Fenglin, Peking University Press, 1997

6. Analytical Chemistry I (Lecture Slides CD ROM) Li Na, Liu Feng, Zhao Fenglin, and Li Ke’an, Peking University Pr ess, 2007

7. Fundamentals of Analytical Chemistry Laboratory (Second Edition). Peking University Analytical Chemistry Teaching Group. Peking University Press, 1997

8. Fundamentals of Analytical Chemistry (Eighth Edition). D. A. Skoog, D. M. West, F. J. Holler, S. R. Crouch, Brooks Cole, 2004

9. Principle of Instrumental Analysis (Fifth Edition), D.A. Sko og, S.R. Stanley, F.J. Holler, Saunders College Publishing/Harcourt Brace College Publishers, 1998

10. Quantitative Chemical Analysis (Forth Edition). I. M. Kolth off, Macmillan, 1969